Deciding to take an antidepressant

A wide range of feelings and beliefs influenced people we interviewed when deciding whether to begin taking an antidepressant. Some believed and trusted their doctor and preferred to be guided by them. Some saw the decision to take the antidepressant as relatively straightforward, while others took a while to decide.

Caroline’s doctor recommended an antidepressant and she was…

Age at interview 60

Gender Female

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An antidepressant can offer the potential to alleviate symptoms and people deciding whether to take a course often say it gives them a sense of relief and hope for the future. Deciding to take an antidepressant can feel like a positive step.

For some, there is an overwhelming motivation to start “tackling the problem” and to do something that could help lift their mood.

The first time Collette was prescribed an antidepressant she said she was willing to try anything that could help with her symptoms and that she wasn’t well enough to think about it too much: “I didn’t want to feel like I was feeling so… yes, why not give it a go? And I really couldn’t be bothered either way, it was just easier to take the pills.”

People talked about “just wanting to feel normal again”, “feeling like I couldn’t carry on”, “needing help straight away” or feeling “desperate” for something that might help.

Others we spoke to took time deciding whether or not to go ahead and said they “wavered”, or “dithered” about it for a while. Some people had always felt they should be able to deal with depression without medical intervention: “it’s a crutch… willpower” and felt that deciding to use an antidepressant was betraying themselves somehow, or giving up (see Feelings about using an antidepressant).

People described balancing “pros and cons” when deciding whether to go ahead, for example, weighing up perceived benefits against fears about side effects, feelings about stigma, or fears that they might become “hooked”.

Lucy X had taken Prozac (fluoxetine) before and wasn’t keen…

Age at interview 21

Gender Female

Age at diagnosis 15

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Gerry tried Cognitive Behaviour therapy…

Age at interview 31

Gender Male

Age at diagnosis 29

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Sometimes even when people had collected their medicines from the pharmacy they did not begin taking the tablets immediately. Reading the list of side effects in the patient information leaflet made some worry that taking an antidepressant might make things worse.

Hannah read the leaflet and was unsure about whether to go ahead because “it says it can cause suicidal feelings – if you weren’t already feeling suicidal is it worth the risk?” (See also The Patient Information leaflet).

Melanie read the leaflet in the packet “front and back to make sure I knew exactly what could happen to me in the course of taking them”.

Greg wondered whether his doctor should have spent more time talking to him before handing him a prescription and after he collected the tablets he kept looking at the box, wondering whether or not to start taking them.

People talked about a range of considerations including uncertainties about how the medicine might make them feel, how long it might take to work, how long they might need to take it, fears about potential side effects, about becoming reliant on medication, or wanting the opportunity to try therapy first.

Even after deciding to go ahead, actually swallowing the tablet for the first time could feel like a big decision. Greg said once you’d decided and taken the tablet you had to have some faith and “believe in it”.

Melanie collected the prescription but took time to read…

Age at interview 44

Gender Female

Age at diagnosis 43

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Greg felt scared about taking the tablet for the first time…

Age at interview 34

Gender Male

Age at diagnosis 34

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Finding out more about the medicines that have been prescribed and talking it through with the GP can help people to decide (see also Finding out more information about antidepressant medicines and Being prescribed an antidepressant).

Andrew was relieved when his doctor diagnosed depression…

Age at interview 50

Gender Male

Age at diagnosis 49

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Hannah spent a week wondering whether to take the…

Age at interview 28

Gender Female

Age at diagnosis 23

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Past experiences of using a particular antidepressant can influence people’s decisions about taking it again. Lou had taken Prozac (fluoxetine) when she was younger; it had increased her anxiety levels and made her feel worse, so when she returned to the GP some years later she told him she was reluctant to take it again. Her doctor explained that she could try others that would not have the same effect.

Lou had the prescription for a while and wasn’t sure she…

Age at interview 39

Gender Female

Age at diagnosis 22

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People can also feel unsure about what to expect, and it can be difficult to make decisions and think things through when you’re experiencing depression (see also Getting to the doctor: seeking help for depression and Being prescribed an antidepressant).

While appointments with GPs increasingly involve shared decisions, we talked to both younger and older people who told us that this hadn’t been the case for them. Olivia Y, for example, said she hadn’t felt she had an opportunity to make a decision as a teenager: “You don’t question it, when a person in front of you is called a doctor you just do it, especially when you’re a child.” Now, though, she says she wants to know more about medicines before deciding whether to take them.

Some older people said they had always believed that the “doctor knows best”. Michael has taken an antidepressant most of his adult life on the advice of his doctors and had been too overwhelmed by his depressive symptoms to be able to make decisions: “I was very accepting, it was just an overall battle to keep going each day, a struggle.”

People who are in hospital with severe depressive symptoms may feel so unwell that they don’t know what medicines they are getting and it can feel as though there is little choice. Olivia X did not agree with her doctor’s diagnosis and refused to take the medicine that he said she needed. Her refusal to comply resulted in a chain of events leading to a hospital admission under a ‘section’ of the Mental Health Act (1983). She felt that decisions about her treatment were effectively removed from her control.

Thomas worried that if he didn’t take the medicines he had been prescribed, that his doctors might commit him to hospital, so while he collected the prescriptions from the chemist he decided not to take them. “I thought if I can be seen to be compliant to treatment it would make me less likely to be sectioned.” (See also Treatment in hospital).

Making decisions about using antidepressant medicines is an ongoing process and people’s views about taking a particular medicine may change over time (see also Managing antidepressants, Stopping taking antidepressants, Changing antidepressants and Reviewing antidepressant use).

Thomas wrote down the positives and negatives…

Age at interview 34

Gender Male

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Being prescribed an antidepressant

The four main groups of antidepressant medicines are Selective serotonin reuptake inhibitors (SSRIs) Serotonin-noradrenaline reuptake inhibitors (SNRIs) Tricyclic antidepressants Monoamine oxidase inhibitors These days an...