As a clinical academic who has been involved with screening for cancer in other sites, he felt he was in a good position to judge (when considering screening for prostate cancer) that the potential for harm outweighed the potential for benefit.

In 2007 Dorothy's doctor found she had an inoperable pancreatic tumour which he suspected was malignant. She is not having treatment now because the doctor said that it wouldn't help much but would harm her quality of life. Dorothy feels quite well.

Marie was diagnosed with chronic lymphocytic leukaemia after pains in her bones and groin. After two years of watch and wait she had several courses of oral chemotherapy with remissions in between. She is currently well but expects further treatment. Marie was also interviewed for the clinical trials section of this site.