Diagnosed three years ago, Ann has tremor in her right hand. The first year after diagnosis was very difficult, but since taking Mirapexin, she feels more able to cope.

• Parkinson's disease - 3-4 years since diagnosis

Although having Parkinson's meant that Judie had to give up work, she has found herself doing all sorts of adventurous things she might never have done otherwise.

Diagnosed 13 years ago, Neil has had GDNF and deep brain stimulation which improved his symptoms. Now he has stiffness, slow walking, and sometimes his speech is affected.

• Parkinson's disease - DBS

Bob was 51 when he was diagnosed. He has tremor in his right hand and is slower at doing things. He continues to work full time.

• Parkinson's disease - 5-7 years since diagnosis

Humphrey was able to continue working as a writer, broadcaster and musician after he was diagnosed. Although his Parkinson's was progressing fairly quickly he maintained a resolutely positive attitude, trying to solve each problem as it presented itself, such as voice recognition software when typing became difficult. He died unexpectedly of a heart attack in 2005.

• Parkinson's disease - 3-4 years since diagnosis

John's symptoms started in 1999. He now has difficulty getting dressed and he is slower with walking, but he is grateful that his symptoms have progressed slowly.