Prostate Cancer

Lack of energy

Many men with prostate cancer feel tired from time to time. One cause can be interrupted sleep when a man has to pass urine frequently during the night. However, radiotherapy and hormone treatment are known to affect energy*. National Institute for Health and Care Excellence (NICE) guidelines 2014 (CG175) recommends that men are told when starting hormone therapy that fatigue is a recognised side effect of this therapy and not necessarily a result of prostate cancer and they should be offered supervised resistance and aerobic exercise at least twice a week for 12 weeks to reduce fatigue and improve quality of life.

Expectations differ; some men reported that their sporting activities had become limited and others regretted that they lacked the energy to work or tackle household and garden chores. One man, who had a radical prostatectomy in 1993, also said that the operation had reduced his stamina and greatly affected his lifestyle.

“Around three in four men with prostate cancer (74 per cent) will have fatigue at some point.” Prostate Charity UK November 2016

*Newer hormone therapies such as bicalutamide (Casodex) are suitable for non-metastatic disease and it does not lower testosterone so patients should not become as lethargic or fatigued.

Last reviewed July 2017.

Last updated July 2017.


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