Prostate Cancer

Hot flushes, breast tenderness and breast enlargement

Many men who had had hormone treatment reported that they suffered from hot flushes. The National Institute for Health and Care Excellence (NICE) recommends medroxyprogesterone as the best treatment for hot flushes or if this is not effective cyproterone acetate or megestrol acetate. Some also said that they had experienced weight gain, breast enlargement, breast tenderness and mood changes. Many men found these symptoms uncomfortable and embarrassing. However, one man said that it was not always an unpleasant experience.

Men who have had both testicles removed or are taking hormone therapy for prostate cancer are at risk of bone thinning (osteoporosis) due to the reduction of testosterone. A DEXA scan can be used to measure bone mineral density and see if bones have become weaker. Weaker bones can lead to an increase risk of bone fractures.

To protect bones a doctor may advise; calcium and vitamin D supplements, to stop smoking, reduce alcohol intake, and take regular weight bearing exercise such as; walking, light weight lifting or dancing.

If men having hormone therapy are diagnosed with osteoporosis they may be offered bisphosphonates or denosumab as a treatment to reduce bone thinning.

Last reviewed July 2017.

Last updated March 2015.


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